Honesty, pricing, process and quality scores appear once 5 customers have rated them.
About Zignagenix
At ZignaGenix, we believe healthcare should be personal, compassionate, and focused on helping people live healthier, more fulfilling lives.Our mission is to improve the quality of life of every patient we serve by providing access to advanced regenerative medicine, innovative wellness therapies, and personalized treatment programs designed to support the body's natural ability to heal and recover.With medical clinics in Tijuana, Puerto Vallarta, and Cancún, Mexico, our experienced physicians and healthcare professionals are dedicated to delivering exceptional patient care, education, safety, and support throughout every step of the treatment journey.We understand that many of our patients come to us after years of searching for answers. That's why we take the time to listen, educate, and develop individualized treatment strategies focused on each patient's unique goals and needs.At ZignaGenix, people come first. Our commitment extends beyond treatments—we strive to create an experience built on trust, integrity, innovation, and genuine care. Every day, we work to help our patients regain hope, restore function, optimize wellness, and achieve a better quality of life.Because when our patients succeed, we succeed.
Zignagenix (zignagenix.com) has 86 customer reviews on Folks Told, with an average rating of 5.0 out of 5.
My name is Lori W and I would like to share my experience with ZignaGenix in Tijuana. I flew into San Diego 27 Sep, spent the night. The driver picked me up the next morning 28 Sep, took me to ZignaGenix where I had one of the scheduled procedures done and the driver took me to the hotel in Tijuana.
I heard feedback of peoples concerns regarding personal safety traveling to Tijuana as my family didn’t want me traveling alone when they found out where I was traveling, but I convinced them I would be fine. During my procedure I forwarded a video of the area which settled my families concerns!! The area in Tijuana which ZinaGenix is located is wonderful, not at all what you hear.
I did have a reaction to the first procedure and I called Ms. Ana, who was very responsive. She immediately sent medication to the hotel. Once I got to the clinic/lab the next day the team took care of me, checking my bloodwork and ensuring my comfort! By the time I left the clinic on the second day, my bloodwork had been checked and I felt great, I did receive the go ahead for my second treatment.
I had three days of treatments and traveled alone, I would do it again!! ZignaGenix is reputable, amazing, and cares about their patients!! Although I traveled by myself, I never felt alone as Ms. Ana was only a phone call away and this was after an extensive welcome letter with comprehensive directions!!! Thank you Ms. Ana, Mr. Carlos, Team, and Mr. Gonzalez (driver), I will see you again 😊
Date of experience was 27-30 September 2026
Reply from ZignagenixOct 5, 2026
Lori, thank you so much for your wonderful 5-star review! We are incredibly happy for you and so proud of you. Traveling on your own for treatment takes a lot of trust and courage, and it meant so much to our entire Zignagenix team to be there for you throughout your journey. We’re grateful you chose us and even more grateful that you felt supported and cared for while you were here. Thank you for trusting us with your care, Lori. We’ll be cheering you on and look forward to hearing about your continued progress! ❤️ — The Zignagenix Team
FM
Fred M.
The service was excellent
The service was excellent, I came all the way from Hawaii, I was met at the San Diego airport and taken to the Hotel. The next morning Ana met me at the hotel for breakfast there after she took me to the border crossing and flew to Porto Vallarta where I was met and taken to a prearranged Resort. The next day I was taken to the clinic where I got my first injection it was a weekend on Monday I was again taken to the clinic for the injection in my knees. The first night I had pain on my right knee , I called and the doctor came at night and brought me pain medicine. Two days later I left. I was not noticing any improvement but was told it could take up to 6 months for the healing process, After 6 months I decided to get knee replacement that was June 2026 I got on the waiting list for the surgery in October but after 7 1/2 months my knees start feeling better, I was not sure if it was for real and I waited 6 weeks and I felt better and I canceled the surgery. I am now able to get up from a chair without using my hands, still not as when I was 50 but much better and after all I am 87years old plus I had a stroke that effected my lower extremities. I hope it will improve more and remains pain free. I am glad I did the Stem Cell therapy and avoided surgery.
Reply from ZignagenixOct 3, 2026
Dear Fred,
We are so happy that the Dr Dezawsa MUSE stem cells helped you avoid surgery and happier yet that it reduced your pain and you can now get around better.
You came to us for severe knee pain and the Dr Dezawa MUSE Stem Cells will also support your heart health as well.
Can't wait to hear more results over time.
Thank you for your trust and kind words!!
Team Zignagenix
DA
D A.
Review of Ryland Dunne and Medical Experience
I traveled to California alone for a medical procedure and chose a package through Ryland Dunne that included a 5-star hotel, airport pickup, transportation to and from my medical procedure, medical and transportation back to the airport.
Given I was traveling alone and did not know anyone in California, having someone meet me at the airport and safely take me to my hotel was especially important to me. Unfortunately, when I arrived, no one was there to pick me up. I contacted Ryland Dunne twice; I received no response. I eventually contacted Mr. Gonzalez, who was scheduled to drive me to my procedure the following morning. He told me he had been instructed that I would take an Uber to the hotel and said he would contact Ryland on my behalf.
My biggest concern no one communicated this change to me. If I had known beforehand, I could have made arrangements. Instead, I arrived in an unfamiliar state alone and was left to figure out how I was to get to my hotel.
The hotel was also disappointing. I paid for a package that was represented as including a 5-star hotel, but the hotel provided was rated 3 stars. When I questioned this, I was told the hotel was chosen to keep me close to the airport. However, since transportation was supposed to be included, I did not understand why the hotel location would prevent those arrangements from being honored.
Unfortunately, throughout the experience, I felt there was an explanation for each issue rather than a solution. The lack of communication and follow-through left me feeling I could not depend on what I had been promised.
I do want to acknowledge the positive aspects of my experience. Mr. Gonzalez, who transported me to and from my procedure, was incredibly kind, professional, and helpful. He was truly a breath of fresh air during what was already a stressful situation.
I also appreciated the response from the Zignagenix Vice President Ms. Suenaga. After learning what had happened, she came to see me on the day of my procedure, expressed her disappointment, and acknowledged how an experience like mine could affect a patient's overall outlook and the company's reputation. She offered a discount on my procedure, which I appreciated and was not expecting.
I am also very grateful to the medical practice and the individuals who made my actual procedure a wonderful experience. My concerns are specifically with the arrangements and communication surrounding the package I purchased through Ryland Dunne.
When someone travels across the country alone for medical treatment, communication, reliability, and follow-through are extremely important.
While I appreciate the individuals who stepped in and helped, the overall experience left me disappointed and feeling that I could not rely on the services I had been promised. Based on this experience, I would not use Mr. Dunne again for future medical treatment arrangements. I sincerely hope Zignagenix takes this feedback seriously and improves its communication, transparency, and follow-through so that other patients do not have a similar experience.
Reply from ZignagenixSep 15, 2026
Thank you for taking the time to share your experience in such detail. We are sincerely sorry that the travel and hotel arrangements surrounding your visit did not meet the expectations that were communicated to you.
Traveling across the country alone for a medical procedure already requires a tremendous amount of trust. When transportation is part of the arrangements, you should not arrive at the airport wondering who is picking you up or how you are getting to your hotel. Regardless of how the misunderstanding occurred, the change should have been clearly communicated to you in advance. We take responsibility for that.
We also understand your disappointment regarding the hotel. If accommodations are represented to a patient in a certain way, what is ultimately provided needs to be consistent with that expectation, or any change needs to be clearly discussed beforehand.
We are grateful that you brought these concerns to our attention and that our Vice President, Anna Karen Suenaga, was able to meet with you personally during your visit. More importantly, your feedback is being used to strengthen our internal processes surrounding transportation, accommodations, communication, and accountability so another patient does not have the same experience.
At the same time, we are especially grateful to hear that Mr. Gonzalez treated you with kindness and professionalism and, most importantly, that you described your actual medical procedure and the care you received from our medical team as a wonderful experience. Our physicians, nurses, and clinical team put an extraordinary amount of care into every patient we treat.
Unfortunately, logistical and communication failures surrounding your travel overshadowed what was otherwise a very positive medical experience. At Zignagenix, however, we recognize that the patient experience begins well before someone walks through our clinic doors. Excellent medical care alone is not enough—the entire experience needs to reflect the same standard.
Thank you for holding us accountable and for also recognizing the individuals who took exceptional care of you. We take your feedback seriously, and we will use it to become better.
— Carlos Ituarte
CEO & Founder
Zignagenix
BM
Brenda M.
I am Brenda Muth from Iowa
I am Brenda Muth from Iowa. I'm 72 years old. I have been in horrible pain in my back and spasms in my back right shoulder. I was on 6 strong pain pills a day! Also my knees were looking deformed from arthritis and was ok'd to have surgery on both , to replace.
I found Zignaggenix after several calls to clinic in America and some in Mexico.
When I called Ana Ituarte, I felt so excited to come to their clinic in T juana Mexico.
Two weeks later , was there. Ana organized my therapy and hotel stay and driver. I came by myself and had no fear because Ana arranged everything , even gave me her private phone number if I had problems! Also, the driver, I had his phone number if I needed him. Everything was perfect!
The clinic was spotless and the team of professionals were amazing! Dr. Oscar asked lots of questions and looked at medical reports from my specialist in America...I had 2 days of stem cells! First day in my thorasic spinal cord ( pretty much painless). Then intervinious stem cells both days too. Second day I got my shoulder and knees done.
The BIG DEAL IS THE LIVE STEM CELLS !!!
The nurses and both dr.s were so professional and kind!
The hotel they brought me to was very clean and the staff help me get my suitcase to the room! Very clean!!! The restaurant there had a free breakfast buffet. I had no worries about cleanliness! I had omletts both days, made to order in front of you, fruit and great coffee and lots of fun dishes!
The last day my ride drive me back over the border and right to my airline. It was all so amazing!
So I have been back for one week...
I was on 6 heavy pain pills for probubly a year and feeling like a zombie when I came... I am taking it easy but I am taking O PAIN PILLS NOW!
(I noticed I can smell really good too. ) Excited to see what 6weeks and 3 and 6 months will bring!!!
IF YOU ARE HESITANT...DO IT! 💖
Reply from ZignagenixSep 15, 2026
Brenda, thank you so much for sharing your story and for trusting Zignagenix with your care.
Reading that you traveled from Iowa to Tijuana by yourself at 72 years old says so much about the trust you placed in our team. From your first conversations with Ana Ituarte, through your transportation, hotel stay, and treatment, our goal was to make sure you felt safe, supported, and cared for every step of the way. We are so happy to hear that Ana and the entire team delivered that experience for you.
We especially appreciate your kind words about Dr. Oscar and our doctors, nurses, drivers, and clinical staff. Providing exceptional medical care is incredibly important to us, but so is how we treat people. We want every patient who walks through our doors to feel that they are being cared for like family.
And hearing that just one week after your treatment you have gone from taking six pain pills a day to currently taking none is wonderful to hear. We know it is still very early, individual results can vary, and healing takes time, so we are equally excited to follow your progress over the coming weeks and months.
Brenda, thank you for allowing us to be part of your journey. Your trust means more to us than you know. Please continue to take good care of yourself, follow your medical team's recommendations, and keep us updated on how you're doing.
We are all cheering for you!
— Carlos Ituarte
CEO & Founder
Zignagenix
VH
Valley H.
Dr Oscar and his whole staff is…
The doctors at this team in clinic is phenomenal. I would suggest this placed to anyone for Stem Cell is fresh never frozen. It comes directly from the hospital. I’d say this is one of the most lead clinics the world for Stem Cell
The staff and the doctors are amazing so knowledgeable made everything easy. The location is lovely. They sent a driver right to the hotel picked us up and took a ride to the clinic. It took us right back. we have had wonderful results from the treatment. Everything we went for has been fixed in a lot more medical problems.
Reply from ZignagenixJun 27, 2026
Thank you for your incredible review and for sharing your experience with our team. We are truly grateful for your trust and kind words about Dr. Oscar, our physicians, and staff.
Our mission is to provide every patient with exceptional care, education, and support throughout their regenerative medicine journey. We're delighted to hear that the transportation, clinic experience, and personalized attention helped make your visit smooth and comfortable.
Most importantly, we are thrilled to hear that you have experienced such meaningful improvements in your health and well-being. Stories like yours inspire our entire team and reinforce our commitment to putting patients first every day.
Thank you again for choosing ZignaGenix and for recommending us to others. We wish you continued health and look forward to being part of your wellness journey for years to come.
Warm regards,
Carlos Ituarte & The ZignaGenix Team
MM
Marie M.
Wonderful drs full of knowledge and…
Wonderful drs full of knowledge and sincerely cared for your well being answered every question with no hesitation helped my autoimmune tremendous made a complete 360 for my well being I couldn’t recommend them enough
Reply from ZignagenixJun 27, 2026
Thank you so much for your wonderful review and for trusting our team with your care. We are honored to hear that our physicians took the time to answer all of your questions and made you feel supported throughout your journey.
Helping patients improve their quality of life is why we do what we do, and it is incredibly rewarding to hear that you experienced such a significant improvement in your autoimmune condition and overall well-being.
Thank you for your recommendation and for being part of the ZignaGenix family. We wish you continued health and look forward to supporting you on your wellness journey for years to come.
– Carlos Ituarte & Team ZignaGenix
ME
Melissa
From the moment the driver picked me…
From the moment the driver picked me up, I knew I was in good hands. I’ve got a spinal cord injury and a TBI, so I’m very cautious with traveling and my surroundings. I’m getting a better quality of life and I’m forever grateful to Zingagenix and everyone who works there. I should add that Manuel goes above and beyond with my texts and calls. Snacks, blankets and so many skilled and compassionate nurses and doctors, I can’t recommend them enough.
Reply from ZignagenixMay 6, 2026
Thank you so much, Melissa. Your words truly mean the world to us. We know how important it is to feel safe, comfortable, and cared for—especially when traveling with a spinal cord injury and TBI—and we’re honored that you trusted ZignaGenix with your care.
From transportation to treatment, our entire team strives to create an experience where patients feel supported every step of the way. We’ll make sure Manuel and the rest of the staff hear your kind words. He genuinely cares deeply about every patient and always goes the extra mile.
We are grateful to be part of your journey toward a better quality of life and we look forward to continuing to support you however we can. Thank you again for your trust and recommendation.
MA
Mike A.
Happy for the experience
Went to Cancun in February for stem cell therapy and now that it’s been almost two months, I can honestly say I feel amazing. The difference didn’t hit all at once, but over time I started noticing more energy, better recovery, and just feeling more like myself again. Lately it feels like I turned the clock back a bit. I’m moving easier, working out consistently, and staying as active as I was in my 20s without feeling worn down after. Even had a few people mention I look younger, which I’ll take.
On top of that, the whole experience was smooth from start to finish. The staff made everything easy, answered every question, and made me feel comfortable the entire time. Everyone was genuinely friendly and professional, which made a big difference being out of the country. Overall I just feel healthier, more motivated, and really glad I decided to do it.
Reply from ZignagenixApr 18, 2026
Mike,
Thank you for sharing such a detailed and thoughtful review—we truly appreciate it.
It’s great to hear how your results have continued to build over time. What you described—more energy, better recovery, and feeling like yourself again—is exactly what we aim for. Hearing that you’re staying active, moving well, and even getting comments about looking younger is incredible.
We’re also glad the entire experience in Cancun felt smooth and comfortable for you. Traveling for care can come with uncertainty, so it means a lot to know our team helped make the process easy, transparent, and professional from start to finish.
Thank you again for trusting us with your care. We’re excited to continue supporting you on your health journey and look forward to hearing more about your progress.
—Team ZignaGenix